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117: Spermidine for a Longer, Healthier Life l How one Holistic Molecule Can Support Longevity, Fertility, Autophagy and so much more!

Oct 25, 2021 | Season 3


We welcome Leslie Kenny, founder of Oxford Healthspan to the show this week. Leslie was told by her doctors that her lupus diagnosis had a life expectancy of five years and that RA could only be managed, not cured. She set out to optimize her health as best she could with safe, natural solutions. Today, at age 56, Leslie is living proof that we can get better with age, so long as we take responsibility for our health and meet our doctors halfway. Spermidine is part of her anti-aging arsenal, and she hopes it will become part of yours too.


0:51 Welcome to the show!

3:19 Leslie Kenny’s Bio

4:55 Welcome Leslie!

6:12 Her health journey to overcome Lupus & RA

10:49 Her return to the doctor’s office

12:45 Her introduction to Regenerative Medicine

13:10 How she discovered Spermidine

16:55 Her version of an Elimination Diet

19:15 Learning to manage stress & recover

20:19 Daily movement & supporting circulation

22:06 Intravenous Immunoglobulin Therapy

21:53 Stress & Chronic “Inflammaging”

22:40 The Spermidine molecule

23:10 Autophagy: your “self-cleaning oven”

25:12 A “holistic molecule” in the body

26:05 Renee’s education on fertility & spermidine

27:02 Research on spermidine & fertility

29:45 How was spermidine discovered?

31:09 It’s role in protecting DNA

31:48 Spermidine in breastmilk

34:33 *Self Decode*

36:02 Spermidine-rich foods

37:38 The concern with wheat germ & PUFAs

39:27 Sleep, circadian rhythm & jet lag

40:04 STUDY: Spermidine & Circadian Rhythm

43:34 How it impacts the GI tract

44:35 Who should take it?

46:56 Cognition, Dementia & Alzheimer’s

48:23 What about wheat & gluten?

50:43 Recommended dose for Primeadine

53:15 Concern with SIBO patients

53:50 How do we know if it’s working?

55:29 Impact on deep sleep scores

56:30 Any biomarkers we can test?

58:33 Her final piece of advice

59:58 Thanks for tuning in!



Website: Primeadine / Oxford Health Span

IG: @primeadine

IG: @lesliesnewprime


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